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Structure activity relationship of uridine 5′-diphosphate analogues at the human P2Y(6) receptor
The structure activity relationships and molecular modeling of the uracil nucleotide-activated P2Y(6) receptor have been studied. A series of UDP analogues bearing substitutions of the ribose moiety, the uracil ring, and the diphosphate group was synthesized and assayed for activity at the human P2Y...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3405152/ https://ncbi.nlm.nih.gov/pubmed/16942026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm060485n |
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