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Interaction of Pseudolaric Acid B with The Colchicine Site of Tubulin

We purified pseudolaric acid B (PAB) from the root and stem bark of Pseudolarix kaempferi (Lindl.) Gorden. Confirming previous findings, we found that the compound had high nanomolar IC(50) antiproliferative effects in several cultured cell lines, causing mitotic arrest and the disappearance of intr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sarkar, Taradas, Nguyen, Tam Luong, Su, Zhi-Wei, Hao, Jun, Bai, Ruoli, Gussio, Rick, Qiu, Samuel X., Hamel, Ernest
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402633/
https://ncbi.nlm.nih.gov/pubmed/22634405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.05.014
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