Interaction of Pseudolaric Acid B with The Colchicine Site of Tubulin

We purified pseudolaric acid B (PAB) from the root and stem bark of Pseudolarix kaempferi (Lindl.) Gorden. Confirming previous findings, we found that the compound had high nanomolar IC(50) antiproliferative effects in several cultured cell lines, causing mitotic arrest and the disappearance of intr...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Sarkar, Taradas, Nguyen, Tam Luong, Su, Zhi-Wei, Hao, Jun, Bai, Ruoli, Gussio, Rick, Qiu, Samuel X., Hamel, Ernest
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402633/
https://ncbi.nlm.nih.gov/pubmed/22634405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.05.014
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky