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Interaction of Pseudolaric Acid B with The Colchicine Site of Tubulin

We purified pseudolaric acid B (PAB) from the root and stem bark of Pseudolarix kaempferi (Lindl.) Gorden. Confirming previous findings, we found that the compound had high nanomolar IC(50) antiproliferative effects in several cultured cell lines, causing mitotic arrest and the disappearance of intr...

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Detaylı Bibliyografya
Asıl Yazarlar: Sarkar, Taradas, Nguyen, Tam Luong, Su, Zhi-Wei, Hao, Jun, Bai, Ruoli, Gussio, Rick, Qiu, Samuel X., Hamel, Ernest
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402633/
https://ncbi.nlm.nih.gov/pubmed/22634405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.05.014
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