Localization of the colchicine-binding site of tubulin.

We have previously shown that rat brain tubulin, a heterodimer consisting of an alpha and beta monomer, can be covalently labeled with [3H]colchicine by near UV irradiation. Most of the label appears in beta-tubulin. We show here that beta-tubulin can be separated and purified from SDS preparative g...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Uppuluri, S, Knipling, L, Sackett, D L, Wolff, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48031/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8265596/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.24.11598
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