Localization of the colchicine-binding site of tubulin.

We have previously shown that rat brain tubulin, a heterodimer consisting of an alpha and beta monomer, can be covalently labeled with [3H]colchicine by near UV irradiation. Most of the label appears in beta-tubulin. We show here that beta-tubulin can be separated and purified from SDS preparative g...

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Main Authors: Uppuluri, S, Knipling, L, Sackett, D L, Wolff, J
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC48031/
https://ncbi.nlm.nih.gov/pubmed/8265596
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