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Localization of the colchicine-binding site of tubulin.

We have previously shown that rat brain tubulin, a heterodimer consisting of an alpha and beta monomer, can be covalently labeled with [3H]colchicine by near UV irradiation. Most of the label appears in beta-tubulin. We show here that beta-tubulin can be separated and purified from SDS preparative g...

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Dettagli Bibliografici
Autori principali: Uppuluri, S, Knipling, L, Sackett, D L, Wolff, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC48031/
https://ncbi.nlm.nih.gov/pubmed/8265596
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