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Characterization of the Colchicine Binding Site on Avian Tubulin Isotype βVI

Tubulin, the basic component of microtubules, is present in most eukaryotic cells as multiple gene products, called isotypes. The major tubulin isotypes are highly conserved in terms of structure and drug binding capabilities. The tubulin isotype βVI, however, is significantly divergent from the oth...

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Détails bibliographiques
Auteurs principaux: Sharma, Shubhada, Poliks, Barbara, Chiauzzi, Colby, Ravindra, Rudravajhala, Blanden, Adam R., Bane, Susan
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852430/
https://ncbi.nlm.nih.gov/pubmed/20178367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100159p
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