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Characterization of the Colchicine Binding Site on Avian Tubulin Isotype βVI

Tubulin, the basic component of microtubules, is present in most eukaryotic cells as multiple gene products, called isotypes. The major tubulin isotypes are highly conserved in terms of structure and drug binding capabilities. The tubulin isotype βVI, however, is significantly divergent from the oth...

詳細記述

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書誌詳細
主要な著者: Sharma, Shubhada, Poliks, Barbara, Chiauzzi, Colby, Ravindra, Rudravajhala, Blanden, Adam R., Bane, Susan
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852430/
https://ncbi.nlm.nih.gov/pubmed/20178367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100159p
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