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Characterization of the Colchicine Binding Site on Avian Tubulin Isotype βVI

Tubulin, the basic component of microtubules, is present in most eukaryotic cells as multiple gene products, called isotypes. The major tubulin isotypes are highly conserved in terms of structure and drug binding capabilities. The tubulin isotype βVI, however, is significantly divergent from the oth...

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Hlavní autoři: Sharma, Shubhada, Poliks, Barbara, Chiauzzi, Colby, Ravindra, Rudravajhala, Blanden, Adam R., Bane, Susan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852430/
https://ncbi.nlm.nih.gov/pubmed/20178367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100159p
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