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An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site

Tubulin dynamics is a promising target for new chemotherapeutic agents. The colchicine binding site is one of the most important pockets for potential tubulin polymerization destabilizers. Colchicine binding site inhibitors (CBSI) exert their biological effects by inhibiting tubulin assembly and sup...

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Detalhes bibliográficos
Main Authors: Lu, Yan, Chen, Jianjun, Xiao, Min, Li, Wei, Miller, Duane D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667160/
https://ncbi.nlm.nih.gov/pubmed/22814904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0828-z
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