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Interaction of Pseudolaric Acid B with The Colchicine Site of Tubulin

We purified pseudolaric acid B (PAB) from the root and stem bark of Pseudolarix kaempferi (Lindl.) Gorden. Confirming previous findings, we found that the compound had high nanomolar IC(50) antiproliferative effects in several cultured cell lines, causing mitotic arrest and the disappearance of intr...

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書誌詳細
主要な著者: Sarkar, Taradas, Nguyen, Tam Luong, Su, Zhi-Wei, Hao, Jun, Bai, Ruoli, Gussio, Rick, Qiu, Samuel X., Hamel, Ernest
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402633/
https://ncbi.nlm.nih.gov/pubmed/22634405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.05.014
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