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Interaction of Pseudolaric Acid B with The Colchicine Site of Tubulin
We purified pseudolaric acid B (PAB) from the root and stem bark of Pseudolarix kaempferi (Lindl.) Gorden. Confirming previous findings, we found that the compound had high nanomolar IC(50) antiproliferative effects in several cultured cell lines, causing mitotic arrest and the disappearance of intr...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3402633/ https://ncbi.nlm.nih.gov/pubmed/22634405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.05.014 |
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