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Interaction of Pseudolaric Acid B with The Colchicine Site of Tubulin

We purified pseudolaric acid B (PAB) from the root and stem bark of Pseudolarix kaempferi (Lindl.) Gorden. Confirming previous findings, we found that the compound had high nanomolar IC(50) antiproliferative effects in several cultured cell lines, causing mitotic arrest and the disappearance of intr...

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Bibliografiset tiedot
Päätekijät: Sarkar, Taradas, Nguyen, Tam Luong, Su, Zhi-Wei, Hao, Jun, Bai, Ruoli, Gussio, Rick, Qiu, Samuel X., Hamel, Ernest
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402633/
https://ncbi.nlm.nih.gov/pubmed/22634405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.05.014
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