Histones from Dying Renal Cells Aggravate Kidney Injury via TLR2 and TLR4

In AKI, dying renal cells release intracellular molecules that stimulate immune cells to secrete proinflammatory cytokines, which trigger leukocyte recruitment and renal inflammation. Whether the release of histones, specifically, from dying cells contributes to the inflammation of AKI is unknown. I...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Allam, Ramanjaneyulu, Scherbaum, Christina Rebecca, Darisipudi, Murthy Narayana, Mulay, Shrikant R., Hägele, Holger, Lichtnekert, Julia, Hagemann, Jan Henrik, Rupanagudi, Khader Valli, Ryu, Mi, Schwarzenberger, Claudia, Hohenstein, Bernd, Hugo, Christian, Uhl, Bernd, Reichel, Christoph A., Krombach, Fritz, Monestier, Marc, Liapis, Helen, Moreth, Kristin, Schaefer, Liliana, Anders, Hans-Joachim
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Nephrology 2012
Gaiak:
Basic Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402284/
https://ncbi.nlm.nih.gov/pubmed/22677551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011111077
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