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Collaborative coupling between polymerase and helicase for leading-strand synthesis

Rapid and processive leading-strand DNA synthesis in the bacteriophage T4 system requires functional coupling between the helicase and the holoenzyme, consisting of the polymerase and trimeric clamp loaded by the clamp loader. We investigated the mechanism of this coupling on a DNA hairpin substrate...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Manosas, Maria, Spiering, Michelle M., Ding, Fangyuan, Croquette, Vincent, Benkovic, Stephen J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401439/
https://ncbi.nlm.nih.gov/pubmed/22434886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks254
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