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Helicase-DNA polymerase interaction is critical to initiate leading-strand DNA synthesis

Interactions between gene 4 helicase and gene 5 DNA polymerase (gp5) are crucial for leading-strand DNA synthesis mediated by the replisome of bacteriophage T7. Interactions between the two proteins that assure high processivity are known but the interactions essential to initiate the leading-strand...

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Detalhes bibliográficos
Main Authors: Zhang, Huidong, Lee, Seung-Joo, Zhu, Bin, Tran, Ngoc Q., Tabor, Stanley, Richardson, Charles C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111293/
https://ncbi.nlm.nih.gov/pubmed/21606333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106678108
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