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Mechanism of strand displacement synthesis by DNA replicative polymerases
Replicative holoenzymes exhibit rapid and processive primer extension DNA synthesis, but inefficient strand displacement DNA synthesis. We investigated the bacteriophage T4 and T7 holoenzymes primer extension activity and strand displacement activity on a DNA hairpin substrate manipulated by a magne...
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Main Authors: | , , , , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Oxford University Press
2012
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401438/ https://ncbi.nlm.nih.gov/pubmed/22434889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks253 |
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