Mechanism of strand displacement synthesis by DNA replicative polymerases

Replicative holoenzymes exhibit rapid and processive primer extension DNA synthesis, but inefficient strand displacement DNA synthesis. We investigated the bacteriophage T4 and T7 holoenzymes primer extension activity and strand displacement activity on a DNA hairpin substrate manipulated by a magne...

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Bibliografische gegevens
Hoofdauteurs: Manosas, Maria, Spiering, Michelle M., Ding, Fangyuan, Bensimon, David, Allemand, Jean-François, Benkovic, Stephen J., Croquette, Vincent
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2012
Onderwerpen:
Nucleic Acid Enzymes
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401438/
https://ncbi.nlm.nih.gov/pubmed/22434889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks253
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