Mechanism of strand displacement synthesis by DNA replicative polymerases

Replicative holoenzymes exhibit rapid and processive primer extension DNA synthesis, but inefficient strand displacement DNA synthesis. We investigated the bacteriophage T4 and T7 holoenzymes primer extension activity and strand displacement activity on a DNA hairpin substrate manipulated by a magne...

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Sonraí Bibleagrafaíochta
Main Authors: Manosas, Maria, Spiering, Michelle M., Ding, Fangyuan, Bensimon, David, Allemand, Jean-François, Benkovic, Stephen J., Croquette, Vincent
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2012
Ábhair:
Nucleic Acid Enzymes
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401438/
https://ncbi.nlm.nih.gov/pubmed/22434889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks253
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