Mechanism of strand displacement synthesis by DNA replicative polymerases

Replicative holoenzymes exhibit rapid and processive primer extension DNA synthesis, but inefficient strand displacement DNA synthesis. We investigated the bacteriophage T4 and T7 holoenzymes primer extension activity and strand displacement activity on a DNA hairpin substrate manipulated by a magne...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Manosas, Maria, Spiering, Michelle M., Ding, Fangyuan, Bensimon, David, Allemand, Jean-François, Benkovic, Stephen J., Croquette, Vincent
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2012
Pynciau:
Nucleic Acid Enzymes
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401438/
https://ncbi.nlm.nih.gov/pubmed/22434889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks253
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