C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2β

Recognition of the proper start codon on mRNAs is essential for protein synthesis, which requires scanning and involves eukaryotic initiation factors (eIFs) eIF1, eIF1A, eIF2 and eIF5. The carboxyl-terminal domain (CTD) of eIF5 stimulates 43S preinitiation complex (PIC) assembly; however, its precis...

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Hlavní autoři: Luna, Rafael E., Arthanari, Haribabu, Hiraishi, Hiroyuki, Nanda, Jagpreet, Martin-Marcos, Pilar, Markus, Michelle A., Akabayov, Barak, Milbradt, Alexander G., Luna, Lunet E., Seo, Hee-Chan, Hyberts, Sven G., Farmy, Amr, Reibarkh, Mikhail, Miles, David, Hagner, Patrick R., O’Day, Eilzabeth M., Yi, Tingfang, Marintchev, Assen, Hinnebusch, Alan, Lorsch, Jon, Asano, Katsura, Wagner, Gerhard
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401385/
https://ncbi.nlm.nih.gov/pubmed/22813744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.04.007
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