C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2β

Recognition of the proper start codon on mRNAs is essential for protein synthesis, which requires scanning and involves eukaryotic initiation factors (eIFs) eIF1, eIF1A, eIF2 and eIF5. The carboxyl-terminal domain (CTD) of eIF5 stimulates 43S preinitiation complex (PIC) assembly; however, its precis...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Luna, Rafael E., Arthanari, Haribabu, Hiraishi, Hiroyuki, Nanda, Jagpreet, Martin-Marcos, Pilar, Markus, Michelle A., Akabayov, Barak, Milbradt, Alexander G., Luna, Lunet E., Seo, Hee-Chan, Hyberts, Sven G., Farmy, Amr, Reibarkh, Mikhail, Miles, David, Hagner, Patrick R., O’Day, Eilzabeth M., Yi, Tingfang, Marintchev, Assen, Hinnebusch, Alan, Lorsch, Jon, Asano, Katsura, Wagner, Gerhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401385/
https://ncbi.nlm.nih.gov/pubmed/22813744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.04.007
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi