C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2β

Recognition of the proper start codon on mRNAs is essential for protein synthesis, which requires scanning and involves eukaryotic initiation factors (eIFs) eIF1, eIF1A, eIF2 and eIF5. The carboxyl-terminal domain (CTD) of eIF5 stimulates 43S preinitiation complex (PIC) assembly; however, its precis...

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Detalhes bibliográficos
Main Authors: Luna, Rafael E., Arthanari, Haribabu, Hiraishi, Hiroyuki, Nanda, Jagpreet, Martin-Marcos, Pilar, Markus, Michelle A., Akabayov, Barak, Milbradt, Alexander G., Luna, Lunet E., Seo, Hee-Chan, Hyberts, Sven G., Farmy, Amr, Reibarkh, Mikhail, Miles, David, Hagner, Patrick R., O’Day, Eilzabeth M., Yi, Tingfang, Marintchev, Assen, Hinnebusch, Alan, Lorsch, Jon, Asano, Katsura, Wagner, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401385/
https://ncbi.nlm.nih.gov/pubmed/22813744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.04.007
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