The eukaryotic initiation factor (eIF) 5 HEAT domain mediates multifactor assembly and scanning with distinct interfaces to eIF1, eIF2, eIF3, and eIF4G

Eukaryotic translation initiation factor (eIF) 5 is crucial for the assembly of the eukaryotic preinitiation complex. This activity is mediated by the ability of its C-terminal HEAT domain to interact with eIF1, eIF2, and eIF3 in the multifactor complex and with eIF4G in the 48S complex. However, th...

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Main Authors: Yamamoto, Yasufumi, Singh, Chingakham Ranjit, Marintchev, Assen, Hall, Nathan S., Hannig, Ernest M., Wagner, Gerhard, Asano, Katsura
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2005
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283452/
https://ncbi.nlm.nih.gov/pubmed/16254050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507960102
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