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Conformational Differences between Two Amyloid β Oligomers of Similar Size and Dissimilar Toxicity
Several protein conformational disorders (Parkinson and prion diseases) are linked to aberrant folding of proteins into prefibrillar oligomers and amyloid fibrils. Although prefibrillar oligomers are more toxic than their fibrillar counterparts, it is difficult to decouple the origin of their dissim...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397903/ https://ncbi.nlm.nih.gov/pubmed/22547072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.329763 |
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