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Role of Helicity on the Anticancer Mechanism of Action of Cationic-Helical Peptides

In the present study, the 26-residue amphipathic α-helical peptide A12L/A20L (Ac-KWKSFLKTFKSLKKTVLHTLLKAISS-amide) with strong anticancer activity and specificity was used as the framework to study the effects of helicity of α-helical anticancer peptides on biological activities. Helicity was system...

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Autores principales: Huang, Yi-Bing, He, Li-Yan, Jiang, Hong-Yu, Chen, Yu-Xin
Formato: Artigo
Lenguaje:Inglês
Publicado: Molecular Diversity Preservation International (MDPI) 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397499/
https://ncbi.nlm.nih.gov/pubmed/22837667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13066849
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