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Tryptophan as a Probe to Study the Anticancer Mechanism of Action and Specificity of α-Helical Anticancer Peptides

In the present study, a single tryptophan, as a fluorescence probe, was shifted from the N-terminus to the middle and to the C-terminus of a 26-residue α-helical anticancer peptide sequence to study the mechanism of action and specificity. The hydrophobicity of peptides, as well as peptide helicity...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Li, Guirong, Huang, Yibing, Feng, Qi, Chen, Yuxin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271632/
https://ncbi.nlm.nih.gov/pubmed/25123187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules190812224
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