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Role of Helicity on the Anticancer Mechanism of Action of Cationic-Helical Peptides
In the present study, the 26-residue amphipathic α-helical peptide A12L/A20L (Ac-KWKSFLKTFKSLKKTVLHTLLKAISS-amide) with strong anticancer activity and specificity was used as the framework to study the effects of helicity of α-helical anticancer peptides on biological activities. Helicity was system...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Molecular Diversity Preservation International (MDPI)
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397499/ https://ncbi.nlm.nih.gov/pubmed/22837667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13066849 |
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