Role of Peptide Hydrophobicity in the Mechanism of Action of α-Helical Antimicrobial Peptides

In the present study, the 26-residue amphipathic α-helical antimicrobial peptide V13K(L) (Y. Chen et al., J. Biol. Chem. 2005, 280:12316-12329, 2005) was used as the framework to study the effects of peptide hydrophobicity on the mechanism of action of antimicrobial peptides. Hydrophobicity was syst...

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Hauptverfasser: Chen, Yuxin, Guarnieri, Michael T., Vasil, Adriana I., Vasil, Michael L., Mant, Colin T., Hodges, Robert S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Mechanisms of Action: Physiological Effects
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855469/
https://ncbi.nlm.nih.gov/pubmed/17158938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00925-06
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