Mapping the HLA-DO/HLA-DM complex by FRET and mutagenesis

HLA-DO (DO) is a nonclassic class II heterodimer that inhibits the action of the class II peptide exchange catalyst, HLA-DM (DM), and influences DM localization within late endosomes and exosomes. In addition, DM acts as a chaperone for DO and is required for its egress from the endoplasmic reticulu...

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Detalhes bibliográficos
Main Authors: Yoon, Taejin, Macmillan, Henriette, Mortimer, Sarah E., Jiang, Wei, Rinderknecht, Cornelia H., Stern, Lawrence J., Mellins, Elizabeth D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396517/
https://ncbi.nlm.nih.gov/pubmed/22733780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113966109
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