HLA-DQ2 interacts atypically with both invariant chain and HLA-DM

Atypical invariant chain (Ii) CLIP fragments (CLIP2) have been found in association with HLA-DQ2 (DQ2) purified from cell lysates. We mapped the binding register of CLIP2 (Ii 96-104) to DQ2 and found proline at the P1 position, in contrast to the canonical CLIP1 (Ii 83-101) register with methionine...

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Autores principales: Fallang, Lars-Egil, Roh, Sujin, Holm, Anders, Bergseng, Elin, Yoon, Taejin, Fleckenstein, Burkhard, Bandyopadhyay, Arunima, Mellins, Elizabeth D., Sollid, Ludvig M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143156/
https://ncbi.nlm.nih.gov/pubmed/18832702
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