HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease

Celiac disease is associated with HLA-DQ2 and, to a lesser extent, HLA-DQ8. Type 1 diabetes is associated with the same DQ molecules in the opposite order and with possible involvement of trans-encoded DQ heterodimers. T cells that are reactive with gluten peptides deamidated by transglutaminase 2 a...

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Main Authors: Tollefsen, Stig, Arentz-Hansen, Helene, Fleckenstein, Burkhard, Molberg, Øyvind, Ráki, Melinda, Kwok, William W., Jung, Günther, Lundin, Knut E.A., Sollid, Ludvig M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1518792/
https://ncbi.nlm.nih.gov/pubmed/16878175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27620
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