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Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease
Celiac disease, also known as celiac sprue, is a gluten-induced autoimmune-like disorder of the small intestine, which is strongly associated with HLA-DQ2. The structure of DQ2 complexed with an immunogenic epitope from gluten, QLQPFPQPELPY, has been determined to 2.2-Å resolution by x-ray crystallo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC384714/ https://ncbi.nlm.nih.gov/pubmed/15020763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306885101 |
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