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CYCLIC AND DIMERIC GLUTEN PEPTIDE ANALOGUES INHIBITING DQ2-MEDIATED ANTIGEN PRESENTATION IN CELIAC DISEASE
Celiac disease is an immune mediated enteropathy elicited by gluten ingestion. The disorder has a strong association with HLA-DQ2. This HLA molecule is involved in the disease pathogenesis by presenting gluten peptides to T cells. Blocking the peptide-binding site of DQ2 may be a way to treat celiac...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2007
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2034199/ https://ncbi.nlm.nih.gov/pubmed/17681795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.07.001 |
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