CYCLIC AND DIMERIC GLUTEN PEPTIDE ANALOGUES INHIBITING DQ2-MEDIATED ANTIGEN PRESENTATION IN CELIAC DISEASE

Celiac disease is an immune mediated enteropathy elicited by gluten ingestion. The disorder has a strong association with HLA-DQ2. This HLA molecule is involved in the disease pathogenesis by presenting gluten peptides to T cells. Blocking the peptide-binding site of DQ2 may be a way to treat celiac...

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Detalhes bibliográficos
Main Authors: Xia, Jiang, Bergseng, Elin, Fleckenstein, Burkhard, Siegel, Matthew, Kim, Chu-Young, Khosla, Chaitan, Sollid, Ludvig M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034199/
https://ncbi.nlm.nih.gov/pubmed/17681795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.07.001
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