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Structure-based design of α-amido aldehyde containing gluten peptide analogues as modulators of HLA-DQ2 and transglutaminase 2

Complete, life-long exclusion of gluten containing foods from the diet is the only available treatment for celiac sprue, a widespread immune disease of the small intestine. Investigations into the molecular pathogenesis of celiac sprue have identified the major histocompatibility complex protein HLA...

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Detalhes bibliográficos
Main Authors: Siegel, Matthew, Xia, Jiang, Khosla, Chaitan
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2041840/
https://ncbi.nlm.nih.gov/pubmed/17590341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.06.020
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