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Transglutaminase 2 Inhibitors and their Therapeutic Role in Disease States

Transglutaminase 2 (TG2) is a multi-domain, multi-functional enzyme that post-translationally modifies proteins by catalyzing the formation of intermolecular isopeptide bonds between glutamine and lysine side-chains. It plays a role in diverse biological functions, including extracellular matrix for...

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Dettagli Bibliografici
Autori principali: Siegel, Matthew, Khosla, Chaitan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1975782/
https://ncbi.nlm.nih.gov/pubmed/17582505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2007.05.003
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