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Transglutaminase 2 Inhibitors and their Therapeutic Role in Disease States
Transglutaminase 2 (TG2) is a multi-domain, multi-functional enzyme that post-translationally modifies proteins by catalyzing the formation of intermolecular isopeptide bonds between glutamine and lysine side-chains. It plays a role in diverse biological functions, including extracellular matrix for...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1975782/ https://ncbi.nlm.nih.gov/pubmed/17582505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2007.05.003 |
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