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Structure-Activity Relationship Analysis of the Selective Inhibition of Transglutaminase 2 by Dihydroisoxazoles

Human transglutaminase 2 (TG2) is believed to play an important role in the pathogenesis of various human disorders including celiac sprue, certain neurological diseases, as well as some types of cancer. Selective inhibition of TG2 should therefore enable further investigation of its role in physiol...

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Autors principals: Watts, R. Edward, Siegel, Mathew, Khosla, Chaitan
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526180/
https://ncbi.nlm.nih.gov/pubmed/17149878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm060839a
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