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Structure-Activity Relationship Analysis of the Selective Inhibition of Transglutaminase 2 by Dihydroisoxazoles

Human transglutaminase 2 (TG2) is believed to play an important role in the pathogenesis of various human disorders including celiac sprue, certain neurological diseases, as well as some types of cancer. Selective inhibition of TG2 should therefore enable further investigation of its role in physiol...

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Bibliografski detalji
Glavni autori: Watts, R. Edward, Siegel, Mathew, Khosla, Chaitan
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526180/
https://ncbi.nlm.nih.gov/pubmed/17149878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm060839a
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