ISSLS PRIZE WINNER: INHIBITION OF NF-κB ACTIVITY AMELIORATES AGE-ASSOCIATED DISC DEGENERATION IN A MOUSE MODEL OF ACCELERATED AGING

STUDY DESIGN: NF-κB activity was pharmacologically and genetically blocked in an accelerated aging mouse model to mitigate age-related disc degenerative changes. OBJECTIVE: To study the mediatory role of NF-κB signaling pathway in age-dependent intervertebral disc degeneration. SUMMARY OF BACKGROUND...

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Detaylı Bibliyografya
Asıl Yazarlar: Nasto, Luigi A., Seo, Hyoung-Yeon, Robinson, Andria R., Tilstra, Jeremy S., Clauson, Cheryl L., Sowa, Gwendolyn A., Ngo, Kevin, Dong, Qing, Pola, Enrico, Lee, Joon Y., Niedernhofer, Laura J., Kang, James D., Robbins, Paul D., Vo, Nam V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395770/
https://ncbi.nlm.nih.gov/pubmed/22343279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BRS.0b013e31824ee8f7
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