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ISSLS PRIZE WINNER: INHIBITION OF NF-κB ACTIVITY AMELIORATES AGE-ASSOCIATED DISC DEGENERATION IN A MOUSE MODEL OF ACCELERATED AGING

STUDY DESIGN: NF-κB activity was pharmacologically and genetically blocked in an accelerated aging mouse model to mitigate age-related disc degenerative changes. OBJECTIVE: To study the mediatory role of NF-κB signaling pathway in age-dependent intervertebral disc degeneration. SUMMARY OF BACKGROUND...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Nasto, Luigi A., Seo, Hyoung-Yeon, Robinson, Andria R., Tilstra, Jeremy S., Clauson, Cheryl L., Sowa, Gwendolyn A., Ngo, Kevin, Dong, Qing, Pola, Enrico, Lee, Joon Y., Niedernhofer, Laura J., Kang, James D., Robbins, Paul D., Vo, Nam V.
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	2012
الموضوعات:	Article
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3395770/ https://ncbi.nlm.nih.gov/pubmed/22343279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BRS.0b013e31824ee8f7
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ISSLS PRIZE WINNER: INHIBITION OF NF-κB ACTIVITY AMELIORATES AGE-ASSOCIATED DISC DEGENERATION IN A MOUSE MODEL OF ACCELERATED AGING

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