Accelerated Aging of Intervertebral Discs in a Mouse Model of Progeria

Intervertebral disc degeneration (IDD) is a common and debilitating disorder that results in reduced flexibility of the spine, pain, and reduced mobility. Risk factors for IDD include age, genetic predisposition, injury, and other environmental factors such as smoking. Loss of proteoglycans (PGs) co...

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Autors principals: Vo, Nam, Seo, Hyoung-Yeon, Robinson, Andria, Sowa, Gwendolyn, Bentley, Douglas, Taylor, Lauren, Studer, Rebecca, Usas, Arvydas, Huard, Johnny, Alber, Sean, Watkins, Simon C., Lee, Joon, Coehlo, Paulo, Wang, Dong, Loppini, Mattia, Robbins, Paul D., Niedernhofer, Laura J., Kang, James
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477798/
https://ncbi.nlm.nih.gov/pubmed/20973062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.21153
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