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Senescent intervertebral disc cells exhibit perturbed matrix homeostasis phenotype
Aging greatly increases the risk for intervertebral disc degeneration (IDD) as a result of proteoglycan loss due to reduced synthesis and enhanced degradation of the disc matrix proteoglycan (PG). How disc matrix PG homeostasis becomes perturbed with age is not known. The goal of this study is to de...
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| Publicado en: | Mech Ageing Dev |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5632945/ https://ncbi.nlm.nih.gov/pubmed/28830687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2017.08.007 |
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