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Cellular senescence in intervertebral disc aging and degeneration

PURPOSE: Age is a major risk factor for multiple disease pathologies, including chronic back pain, which stems from age-related degenerative changes to intervertebral disc tissue. Growing evidence suggest that the change in phenotype of disc cells to a senescent phenotype may be one of the major dri...

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Detalhes bibliográficos
Publicado no:Curr Mol Biol Rep
Main Authors: Patil, Prashanti, Niedernhofer, Laura J., Robbins, Paul D., Lee, Joon, Sowa, Gwendolyn, Vo, Nam
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248341/
https://ncbi.nlm.nih.gov/pubmed/30473991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40610-018-0108-8
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