Attenuation of ataxia telangiectasia mutated signalling mitigates age‐associated intervertebral disc degeneration

Previously, we reported that persistent DNA damage accelerates ageing of the spine, but the mechanisms behind this process are not well understood. Ataxia telangiectasia mutated (ATM) is a protein kinase involved in the DNA damage response, which controls cell fate, including cell death. To test the...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Han, Yingchao, Zhou, Chao‐Ming, Shen, Hongxing, Tan, Jun, Dong, Qing, Zhang, Lei, McGowan, Sara J., Zhao, Jing, Sowa, Gwendolyn A., Kang, James D., Niedernhofer, Laura J., Robbins, Paul D., Vo, Nam N.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406969/
https://ncbi.nlm.nih.gov/pubmed/32567210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13162
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