Attenuation of ataxia telangiectasia mutated signalling mitigates age‐associated intervertebral disc degeneration

Previously, we reported that persistent DNA damage accelerates ageing of the spine, but the mechanisms behind this process are not well understood. Ataxia telangiectasia mutated (ATM) is a protein kinase involved in the DNA damage response, which controls cell fate, including cell death. To test the...

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書目詳細資料
發表在:Aging Cell
Main Authors: Han, Yingchao, Zhou, Chao‐Ming, Shen, Hongxing, Tan, Jun, Dong, Qing, Zhang, Lei, McGowan, Sara J., Zhao, Jing, Sowa, Gwendolyn A., Kang, James D., Niedernhofer, Laura J., Robbins, Paul D., Vo, Nam N.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2020
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Original Papers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406969/
https://ncbi.nlm.nih.gov/pubmed/32567210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13162
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