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Senescent intervertebral disc cells exhibit perturbed matrix homeostasis phenotype
Aging greatly increases the risk for intervertebral disc degeneration (IDD) as a result of proteoglycan loss due to reduced synthesis and enhanced degradation of the disc matrix proteoglycan (PG). How disc matrix PG homeostasis becomes perturbed with age is not known. The goal of this study is to de...
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| Udgivet i: | Mech Ageing Dev |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5632945/ https://ncbi.nlm.nih.gov/pubmed/28830687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2017.08.007 |
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