Accelerated Aging of Intervertebral Discs in a Mouse Model of Progeria

Intervertebral disc degeneration (IDD) is a common and debilitating disorder that results in reduced flexibility of the spine, pain, and reduced mobility. Risk factors for IDD include age, genetic predisposition, injury, and other environmental factors such as smoking. Loss of proteoglycans (PGs) co...

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Hauptverfasser: Vo, Nam, Seo, Hyoung-Yeon, Robinson, Andria, Sowa, Gwendolyn, Bentley, Douglas, Taylor, Lauren, Studer, Rebecca, Usas, Arvydas, Huard, Johnny, Alber, Sean, Watkins, Simon C., Lee, Joon, Coehlo, Paulo, Wang, Dong, Loppini, Mattia, Robbins, Paul D., Niedernhofer, Laura J., Kang, James
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477798/
https://ncbi.nlm.nih.gov/pubmed/20973062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.21153
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