Mitochondrial-derived reactive oxygen species (ROS) play a causal role in aging-related intervertebral disc degeneration

Oxidative damage is a well-established driver of aging. Evidence of oxidative stress exists in aged and degenerated discs, but it is unclear how it affects disc metabolism. In this study, we first determined whether oxidative stress negatively impacts disc matrix metabolism using disc organotypic an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nasto, Luigi A., Robinson, Andria R., Ngo, Kevin, Clauson, Cheryl L., Dong, Qing, St. Croix, Claudette, Sowa, Gwendolyn, Pola, Enrico, Robbins, Paul D., Kang, James, Niedernhofer, Laura J., Wipf, Peter, Vo, Nam V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668354/
https://ncbi.nlm.nih.gov/pubmed/23389888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22320
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak