LAHEDES: the LAGLIDADG homing endonuclease database and engineering server

LAGLIDADG homing endonucleases (LHEs) are DNA cleaving enzymes, also termed ‘meganucleases’ that are employed as gene-targeting reagents. This use of LHEs requires that their DNA specificity be altered to match sequences in genomic targets. The choice of the most appropriate LHE to target a particul...

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Autori principali: Taylor, Gregory K., Petrucci, Lucas H., Lambert, Abigail R., Baxter, Sarah K., Jarjour, Jordan, Stoddard, Barry L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394308/
https://ncbi.nlm.nih.gov/pubmed/22570419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks365
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