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Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins
Homing endonucleases (HEs) cut long DNA target sites with high specificity to initiate and target the lateral transfer of mobile introns or inteins. This high site specificity of HEs makes them attractive reagents for gene targeting to promote DNA modification or repair. We have generated several hu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2655683/ https://ncbi.nlm.nih.gov/pubmed/19153140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp004 |
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