Prospective Screening of Novel Antibacterial Inhibitors of Dihydrofolate Reductase for Mutational Resistance

Lignende værker

• Towards the understanding of resistance mechanisms in clinically isolated trimethoprim-resistant, methicillin-resistant Staphylococcus aureus dihydrofolate reductase
  af: Frey, Kathleen M., et al.
  Udgivet: (2009)
• Structure-Based Approach to the Development of Potent and Selective Inhibitors of Dihydrofolate Reductase from Cryptosporidium
  af: Bolstad, David B., et al.
  Udgivet: (2008)
• Crystal Structures of Wild-type and Mutant Methicillin-resistant Staphylococcus aureus Dihydrofolate Reductase Reveal an Alternative Conformation of NADPH that may be Linked to Trimethoprim Resistance
  af: Frey, Kathleen M., et al.
  Udgivet: (2009)
• Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligand-induced conformational changes shared among species
  af: Paulsen, Janet L., et al.
  Udgivet: (2013)
• Synthetic and Crystallographic Studies of a New Inhibitor Series Targeting Bacillus anthracis Dihydrofolate Reductase
  af: Beierlein, Jennifer M., et al.
  Udgivet: (2008)