Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis: Dihydropyridopyrazole Analogues of Podophyllotoxin

[Image: see text] A three-component condensation of 5-amino-3-methylpyrazole, tetronic acid and various aromatic, heteroaromatic and aliphatic aldehydes leads to the formation of dihydropyridopyrazole analogues of a cytotoxic lignan podophyllotoxin. This new heterocyclic scaffold-based library allow...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Magedov, Igor V., Manpadi, Madhuri, Rozhkova, Elena, Przheval’skii, Nikolai M., Rogelj, Snezna, Shors, Scott T., Steelant, Wim F. A., Van slambrouck, Severine, Kornienko, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393043/
https://ncbi.nlm.nih.gov/pubmed/17188868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.11.095
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados