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The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments
In the course of apoptosis, activated caspases cleave ∼500 to ∼1,000 different proteins in a mammalian cell. The dynamics of apoptosis involve a number of previously identified, caspase-generated proapoptotic protein fragments, defined as those that increase the probability of apoptosis. In contrast...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390858/ https://ncbi.nlm.nih.gov/pubmed/22670058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207786109 |
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