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Glutamine-Specific N-Terminal Amidase, a Component of the N-End Rule Pathway

Deamidation of N-terminal Gln by Nt(Q)-amidase, a previously undescribed N-terminal amidohydrolase, is a part of the N-end rule pathway of protein degradation. We detected the activity of Nt(Q)-amidase, termed Ntaq1, in mouse tissues, purified Ntaq1 from bovine brains, identified its gene, and began...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Haiqing, Piatkov, Konstantin I., Brower, Christopher S., Varshavsky, Alexander
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749074/
https://ncbi.nlm.nih.gov/pubmed/19560421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.04.032
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