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Aminoacyl-transferases and the N-end rule pathway of prokaryotic/eukaryotic specificity in a human pathogen

The N-end rule relates the in vivo half-life of a protein to the identity of its N-terminal residue. Primary destabilizing N-terminal residues (Nd(p)) are recognized directly by the targeting machinery. The recognition of secondary destabilizing N-terminal residues (Nd(s)) is preceded by conjugation...

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Detalhes bibliográficos
Main Authors: Graciet, Emmanuelle, Hu, Rong-Gui, Piatkov, Konstantin, Rhee, Joon Haeng, Schwarz, Erich M., Varshavsky, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413915/
https://ncbi.nlm.nih.gov/pubmed/16492767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511224103
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