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Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway
The first step of the hierarchically organized Arg/N-end rule pathway of protein degradation is deamidation of the N-terminal glutamine and asparagine residues of substrate proteins to glutamate and aspartate, respectively. These reactions are catalyzed by the N-terminal amidase (Nt-amidase) Nta1 in...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5098633/ https://ncbi.nlm.nih.gov/pubmed/27791147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612620113 |
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