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Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway

The first step of the hierarchically organized Arg/N-end rule pathway of protein degradation is deamidation of the N-terminal glutamine and asparagine residues of substrate proteins to glutamate and aspartate, respectively. These reactions are catalyzed by the N-terminal amidase (Nt-amidase) Nta1 in...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kim, Min Kyung, Oh, Sun Joo, Lee, Byung-Gil, Song, Hyun Kyu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098633/
https://ncbi.nlm.nih.gov/pubmed/27791147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612620113
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