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N-Terminal Acetylation-Targeted N-End Rule Proteolytic System: The Ac/N-End Rule Pathway

Although Nα-terminal acetylation (Nt-acetylation) is a pervasive protein modification in eukaryotes, its general functions in a majority of proteins are poorly understood. In 2010, it was discovered that Nt-acetylation creates a specific protein degradation signal that is targeted by a new class of...

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Pubblicato in:Mol Cells
Autori principali: Lee, Kang-Eun, Heo, Ji-Eun, Kim, Jeong-Mok, Hwang, Cheol-Sang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society for Molecular and Cellular Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794598/
https://ncbi.nlm.nih.gov/pubmed/26883906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2016.2329
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