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Calpain-generated natural protein fragments as short-lived substrates of the N-end rule pathway
Calpains are Ca(2+)-dependent intracellular proteases. We show here that calpain-generated natural C-terminal fragments of proteins that include G protein–coupled receptors, transmembrane ion channels, transcriptional regulators, apoptosis controllers, kinases, and phosphatases (Phe-GluN2a, Lys-Ica5...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3948289/ https://ncbi.nlm.nih.gov/pubmed/24550490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401639111 |
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